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By Zen Zheng
HOUSTON, Feb. 12 (Xinhua)-- Woo-digada! Woo-digada! Woo-digada! Woo-digada! The constant, rapid noise from Cynthia McGuffie's backpack can be jarring to one who first hears it. But to her it sounds like some Caribbean-rhythm drummed briskly on a conga.
"It's my heartbeat; It's my life. I can't live without it now," 55-year-old McGuffie, who has the backpack with her day and night, told Xinhua in a recent exclusive interview.
The backpack holds a battery-driven device connected to her chest via tubings, which powers a total artificial heart recently implanted in her at Baylor St. Luke's Medical Center, a hospital in the Texas Medical Center, the world's largest medical center in Houston in the southern state of Texas. The computerized device, known as the driver, also monitors her blood flow.
"I can do so many things that I couldn't before. I can move around; I can walk, and even jog," said the petite, bright-eyed McGuffie who received the 50cc SynCardia Total Artificial Heart, the latest, smaller man-made heart developed by the American company SynCardia Systems.
With her heart beginning to fail three years ago, McGuffie lost her ability to work and had to rely on a pacemaker. As her heart rapidly deteriorated, in spring 2016, she was admitted to Baylor St. Luke's, home to the Texas Heart Institute, a prestigious cardiology and heart surgery facility founded by the late, world-renowned heart surgeon Dr. Denton Cooley, best known for his successful first human heart transplant in the U.S. in 1968 and the world's first total artificial heart implantation in 1969. There, McGuffie was diagnosed with end-stage biventricular heart failure and put on a donor heart transplant waiting list.
Months had passed and no suitable organ was available for McGuffie due to her small frame and high antibody count in her blood. Given only days to weeks to live, she was told her only hope was implantation of the 50cc SynCardia, a brand-new artificial heart designed for those with small stature, which is approved only for clinical trial by the U.S. Food and Drug Administration.
McGuffie jumped at her only chance of survival.
"I was surprised that I had this option. My family wanted me to live, and I wanted to live, too," she said.
It took heart surgeon Dr. Jeffery Morgan more than five hours to complete the procedure on McGuffie. Within days, she was sitting up in bed, and in less than two months became the first in Texas and third in the U.S. discharged from a hospital with an implanted 50cc SynCardia, a smaller version of its processor, the 70cc SynCardia.
"She would have died had she not received the artificial heart," said Morgan, surgical director of Mechanical Circulatory Support and Cardiac Transplant of the Texas Heart Institute and chief of Cardiothoracic Transplant and Circulatory Support at Baylor College of Medicine.
"She has much more energy, is no longer short of breath, and candoactivities of daily living," Morgan told Xinhua recently. "She has no signs of heart failure, nor any device-related complications such as bleeding, infection or stroke."
Her husband Ed McGuffie was surprised at her fast recovery. For the family, the round-the-clock white noise from the backpack is music to the ear, a happy reminder of her presence.
"We're so grateful she's still with us; she's got her life back with this surgery," he said to Xinhua.
The artificial heart serves as a transition to an eventual donor heart - given an appropriate organ becomes available - or a device for long-term use by one who isn't a candidate for transplant. McGuffie remains hopeful of getting a transplant one day.
Morgan said that her prognosis is good.
"Patients like her live for years on the SynCardia device," he said, describing the device as "a monumental leap forward" in artificial heart technology.