Granite Male Enhancement CBD oil begins with the extraction of CBD from the Cannabis sativa plant. However, when CBD and hempseed oil are put side by side, a lot of misleading labeling happens. Cannabidiol, along with a number of other chemicals found in cannabis plants, work naturally with a mammal's cannabinoid receptor sites, which make up the endocannabinoid system (ECS) and which are found primarily in the brain and central nervous system.